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On-Demand

CSEM Stream

CSEMS2 - Harold Copp Basic Science Lecture: Osteogenesis Imperfecta: Mechanisms, Models, and Therapeutic Implications

Thursday, November 27, 2025
16:00 - 17:00 Toronto
Location: Room 205

    Speaker(s)

  • Frank Rauch, MD

    Montreal, Quebec, Canada

    Disclosure(s): Angitia: Advisory Board (Ongoing); Biomarin: Advisory Board (Ongoing)

    • Moderator(s)

  • Sara Awad, MD (she/her/hers)

    Associate professor
    Queen's University
    Queen’s university
    Kingston, Ontario, Canada

    Disclosure(s): I do not have a relationship with a for-profit and/or a not-for-profit organization to disclose

Disclosure(s):
Frank Rauch, MD: Angitia: Advisory Board (Ongoing); Biomarin: Advisory Board (Ongoing)
Learning Objectives: This session will:
1. Discuss the latest research on genetic and molecular mechanisms osteogenesis imperfecta (OI) and the implications on bone matrix development and skeletal fragility using animal models.
2. Evaluate the genetic testing, imaging modalities and biomarkers of bone turnover for diagnosis and monitoring of OI and related phenotypes of metabolic bone disease.
3. Assess current and emerging advances in technologies and therapeutic approaches for treatment of OI.