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Michael B. Wheeler, PhD

Professor
University of Toronto
Etobicoke, Ontario, Canada

Mike Wheeler is a full professor of Medicine, in the Departments of Medicine and Physiology, University of Toronto, Faculty of Medicine. His research is focused on developing novel strategies to detect and treat diabetes using multidisciplinary approaches, which combine information gained from genetic models of diabetes, genomics/proteomics, molecular biology, and pancreatic islet biology. He is currently investigating several avenues of research that explore pancreatic islet function in humans in both healthy and diseased states. Relevant to his presentation, a major thrust of his research involves utilizing metabolomic, lipidomic and proteomic approaches to uncover the underlying pathophysiology of Gestational Diabetes Mellitus (GDM) and the transition to Type 2 diabetes later in life. In the past 9 years, in collaboration with Dr. Erica Gunderson of Kaiser Permanente, he has examined future diabetes risk and pathology in a cohort of women with a history of GDM. The Study of Women, Infant Feeding and Type 2 Diabetes after Gestational Diabetes (SWIFT) is a prospective cohort of women with GDM that conducted in-person research exams, with ongoing follow up for incident T2D through 2025. Dr. Wheeler has published extensively on SWIFT, discovering early underlying pathology associated with future T2D onset and on metabolic and proteomic signatures that increase the precision to assess future T2D risk after a GDM pregnancy.

Disclosure(s): I do not have a relationship with a for-profit and/or a not-for-profit organization to disclose

Presentation(s):